If you think about installing Mac OS X on a case-sensitive volume, don’t do it. Although OS X works fine on a case-sensitive volume, however third-party software not necessarily.
For example you cannot install software like Adobe Photoshop CS3 or Age of Empires III on a case-sensitive filesystem. (I know only about that two) Adobe and Microsoft don’t write anything about filesystem requirement in software requirements at the box or even documentation. Why?!
Age of Empires III cannot be played on a Case-sensitive formatted volume. For more information, please consult the game’s Read Me file.
On Adobe support page I found solution, but it doesn’t work… The solution is to install software on a case-insensitive volume. When you create second partition with a case-insensitive volume and try to install software there, nothing will happen. You cannot install still.
This is not the first time when I get lesson from OS X that only its defaults are right…